JOJ Nursing & Health Care

Accentuated Rehabilitation Recovery from Spinal Cord Injury in Rats through Increased Behavioral Activity besides Minocycline Treatment: A Nursing Care Perspective

Author: Mohammad Ahmad*, Ahmad Abo Shaiqah, Abdualrahman Saeed Alshehri and Abdulaziz Moadi Alotaibi

Published: November 22, 2018

DOI: 10.19080/JOJNHC.2017.05.555674

Abstract Content: The present study aimed at developing improved rehabilitative intervention which can accentuate known therapeutical treatment for a better functional recovery from spinal cord injury (SCI). Furthermore, this research intends to utilize the passion of nursing care by bringing awareness among nurses for SCI patient?s care and opening avenues and interests in nursing research also. Young adult male rats were subjected to spinal injury and were allocated to five groups with eight animals in each, viz. Group 1 as normal uninjured control; group 2 as sham control; group 3 as SCI group with spinal injury; group 4 as SCI treated group A that were same as group 3 but were treated with a daily injection of Minocycline (50mg/kg) for 29 days and subjected to BBB behavioral test every alternate days; group 5 as SCI treated group B that were same as group 4 except that the animals were subjected to a daily enforced extra 5 tasks in same sequence as for exercises in BBB test. Minocycline had an attenuating effect on SCI in both treated groups A and B, however, the recovery in Group-B was observed to be significantly (p<0.001) greater than Group-A. It is concluded that enforced behavioral exercises in addition to drug treatment can enhance functional recovery. Furthermore, the present study can encourage the nurses to develop their nursing skills for SCI rehabilitation and their research abilities.