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Cured with Renal Sympathetic Denervation and Nephropexy (RSD&N) Surgery: Case Report
Loin Pain and Haematuria Syndrome (LPHS) Complicating Symptomatic Nephroptosis (SN), Cured with Renal Sympathetic Denervation and Nephropexy (RSD&N) Surgery: Case Report
Ahmed N Ghanem1*, Khalid A Ghanem2, Nisha Pindoria3 and Salma A Ghanem4
1Consultant Urologist Surgeon, Egypt
2Mansoura University Hospital, Egypt
3North Middlesex University Hospital, London
4Royal London Hospital, London
Submission: October 30, 2018;Published: November 30, 2018
*Corresponding author: Ahmed N Ghanem, MD, FRCS, Consultant Urologist Surgeon, No1 President Mubarak Street, Mansoura 35511, Egyp
How to cite this article: Ahmed N G, Khalid A G, Nisha P, Salma A G. Loin Pain and Haematuria Syndrome (LPHS) Complicating Symptomatic
Nephroptosis (SN), Cured with Renal Sympathetic Denervation and Nephropexy (RSD&N) Surgery: Case Report. Open Access J Surg. 2018; 10(1): 555779. DOI: 10.19080/OAJS.2018.10.555779.
Introduction and objective: To report a case demonstrating the link of LPHS with SN is that is based on IVU7 sign and retrograde pyelography. Renal Sympathetic denervation and Nephropexy (RSD&N) Surgery has proved curable for the condition
Patient and methods: The reported case in which IVU with erect film shows the IVU7 sign is measure of renal pedicle stretch. Retrograde pyelography (RGP) showed the internal renal damage while all ancillary imaging was normal. The surgery of RSD&N was used for treatment of the condition.
Results: An IVU with erect film and RGP detected the diagnosis and the renal pathology while no other imaging could. Comparing IVU supine and erect revealed the IVU7 sign which is a measure of renal pedicle stretch causing artery stenosis and ischaemia. The findings on RGP show erosion of renal papillae and leakage of contrast medium into renal veins which is the site of hamaturia. The surgery of RSD&N cured the condition.
Conclusion: An IVU with erect film and RGP clinched the diagnosis and revealed the renal pathology while no other imaging could. It should be essential diagnostic investigation in every LPHS case. The surgery of RSD&N cured the condition.
The link of SN with LPHS is a new discovery explaining its real patho-etiology [1,2]. Although SN is known for centuries, it was disparaged >70 years ago and omitted from all textbooks. Standard imaging protocol is constantly normal- at supine posture. Intravenous urography with erect film (IVU-E) has been made obsolete and is not requested, hence chance diagnosis of SN is unlikely, and diagnosis is easily missed. Many of SN features and some complications were documented >70 years ago , but it was disparaged soon afterwards . The LPHS was reported in 19675. Here we report an illustrative case report showing the link of LPHS with SN.
A 28 years old girl was regularly admitted via Accident
and Emergency department with severe loin pain and gross
haematuria over a period of 3 years. Her repeated investigations
including urine culture, IVU and CT scan were all normal
when done at supine posture. An IVU-E was later done and
demonstrated her overlooked SN (Figure 1). The internal renal
damage explaining haematuria was revealed by the IVU7 sign
(Figure 2) and on retrograde pyelography (RGP) (Figure 3). She
consented for surgery and open renal sympathetic denervation
and nephropexy (RSD & N) was performed on her right kidney.
She was cured of both LPHS and SN.
The presented case report clearly demonstrates the LPHS
complicates SN. The renal damage is caused by pedicle stretch
causing renal ischaemia as shown on IVU7 sign (Figure 2). The
internal renal damage causing pain and haematuria is best shown
on RGP (Figure 3). Unfortunately, no other investigation including
CT and MRI can reveal the pathology of LPHS complicating
SN. Upright IVU is currently undone and has not been reported
previously in LPHS. Retrograde pyelography findings (Figure 3)
have not previously been documented in either condition. The use
of IVU started early in the 20th century while clinical evidence on
the genuineness of SN pain dated back to the 15th century. Loin
pain hematuria syndrome was reported in 1967  while Dietl’s
crisis is known for centuries. Organic reno-vascular complications
demonstrated on conventional arteriography of SN and LPHS are
of advanced cases. In view of the new evidence presented here
and previously [1,2], the authorities should reconsider SN with
link to LPHS and bring it back to current textbooks.