Research Article

Nano Pathology of Sheikh’s Syndrome

Shahid Sheikh H*

Institute of Genomic Treatment & Research Center, 8th Floor, zenith plaza, Bahria Town, Karachi, Pakistan

Submission: June 24, 2024; Published: August 15, 2024

*Corresponding author: Shahid Sheikh H, Institute of Genomic Treatment & Research Center, 8th Floor, zenith plaza, Bahria Town, Karachi, Pakistan

How to cite this article: Shahid Sheikh H*. Nano Pathology of Sheikh’s Syndrome. JOJ Ophthalmol. 2024; 11(3): 555813. DOI: 10.19080/JOJO.2024.11.555813

Keywords: Cyto-Pathology; Atomic Force Microscopy; Symptomatic Relief/Treatment; Diagnoses; Covid 19; Teenage Drug Addiction

Introduction

Conventionally, the understanding of any given human ailment aligns from system to organ to tissues to cells. We call it “Cyto-Pathology”, we engage in a variety of diagnostic tools to evidence such cyto-pathology to confirm our diagnoses and tailor a medical or surgical plan according to the given established protocols.

Atomic Force Microscopy (AFM) has brought a new paradigm in the view to best clear our understanding of the emerging patho-physiology of a given symptomatic pathology. No more we can logically treat a disease based on the symptomatic realm, admitting “Etiology Unknown”.

Today, majority of the ailments have only symptomatic relief/treatment. There is an urgency to take a deeper look at the source of ailments and try to define the possible etiology. We all are familiar with the Nucleus of a given cell being the controlling entity for that cell’s homeostasis, timely development and its functions.

So is true of the controlling Neurons of the Brain. In 2004, Late Dr. Edward Wagoner and his team at the University of California at Irvine did not fathom the idea that they are about to change a whole new paradigm. His team Dr. Alex Malkin, Dr. Alex McPhearson and Dr. Marco Plomp used the AFM and revealed the real time “Nano-Pathological” series of events that Dr. Wagoner reported in his last paper. I was fortunate to have this opportunity to evaluate their findings clinically and integrate into the clinical practice to best diagnose and help alleviate the symptoms and pathoneogenesis, that help prevail the homeostasis of cells, tissues, organs, system that promote the quality of life. Cyto-pathology is no longer an absolute reliable tool to finalize the proper diagnoses.

Currently, so called treatments are merely a symptomatic pacification to borrow time for the resident immune system to recongregate/ revitalize against the pathogens in question.

The Nucleo-pathology of the controlling neurons indeed is the paradigm shift, the grass root Instigator of the basic symptomatology that results into the disruption of the normal homeostasis. On the contrary it is the opportunity given to the pathophysiology to continue to grow the bigger challenge.

To date, this phenomenon has been a hidden secret of nature. Now that is opened, it is unraveling the possible etiologies of the unknown nature of the conventional diseases. The “Sheikh’s Syndrome”, is rightfully a very well established guideline to see any disease’s root cause etiology and possible treatment to eradicate the ailment.

In the nucleus, the resident DNA with its helix attached and series of RNA attached has no room for another viral or bacterial DNA or RNA to co-exist or to co-habitate and maintain the functional homeostasis. Though viral genome might have entered the nucleus 6 months before birth. If the weaker viral genome survived the normal delivery of the newborn, effecting some stages of the developmental processes. If not resulted into a miscarriage.

If mother’s resident immunity does not warrant to defend against it, the miscarriage can take place. The use of antiviral should be seriously considered to save two lives during pregnancy. Survived viral genome tries to invade the physiology of the nucleus in the following manner. Its Alpha mRNA leave the nucleus to hunt for lipoprotein molecule and translate itself into Alpha protein & re-attach itself to same place.

Similarly, Beta messenger RNA’S do the same and translate into beta proteins to reattach itself where originated from [1]. No sooner, this process of proteinization completes, the proliferation of the whole genome begins. This is the basic and vital process prior to the start of the proliferation. If any functional neuron is dealing with the invaded Nucleus by any viral genome. Then the resident immunity remains at work to retard/incapacitate the viral genome continuously [2]. Any virus from the exposure to the infection must survive this proteinization process before proliferating itself to cause infection [1,3].

Covid 19 virus has to go through this same survival mode prior to the start of an infection. Proteinization of its Alpha & Beta messenger RNA can be stopped, prior to its proliferation. It’s true for any virus. COVID 19, [4] DENGUE, CONGO, EBOLA, MERS OR any other virus.

We have found the positive results for many ailments among the following and some are left for further investigation.

•ADD *Allergies *Alzheimer •Amenorrhea *Anemia

*Aneurysms •Atherosclerosis *Asthma *Bell’s & Cerebral Palsy

•CAD *Cancer *CFS •Cognitive Disorder

*Chromosomal Disorder *Diabetes Mellitus •Encephalitis *Endocrine

Disorders *Gastroenteritis •Gastric Ulcer * Gynecomastia

*Hypertension •Hypohemoglobinemia * Hyperlipidemia

* Hypothalamic Dysf. •Hypo/ hyperthyroidism * Impotence * Infertility

•IBS * Liver Dysf. * Meningitis •Metabolic Disorder

*M.S. * Neoplastic-Tumors •Neuralgia *Neuropathy *Nephropathy •Parkinson’s Pituitary Dysfunctions

•Recurrence of Minor Infections •Sudden Tachycardia

* Schizophrenia * Respiratory Failure •Stroke *Teenage Drug Addiction.

References

1. Plomp M, McPherson A, Malkin A (2002) Atomic Force Microscopy. AJP 160(6).
2. John Vella P, Alexander Wiseman C (2019) Nephrology self-assessment program: Neph SAP 18(5): 297-302.
3. Bernard Moss, Ehud Katz (1969) Synthesis of vaccinia viral proteins in cytoplasmic extracts. II. Identification of early and late viral proteins. J Virol 4(5): 596-602.
4. Yong Wah Tan, Hongyuan Shen (2017) Coronavirus infectious bronchitis virus non-structural proteins 8 and 12 form stable complex independent of the non-translated regions of viral RNA and other viral proteins. Virology 513: 75-84.