Inverse Schizophrenia in the Context of Entropy
of Neural and Glial Network of the Brain
Physician of functional diagnostics of SBIH, Russia
Submission: November 20, 2018;Published: November 27, 2018
*Corresponding author: Rosman SV, Physician of functional diagnostics of SBIH, Regional psychoneurological clinic, Russia
How to cite this article: Rosman SV. Inverse Schizophrenia in the Context of Entropy of Neural and Glial Network of the Brain . Glob J Add & Rehab Med. 2018; 6(2): 555685. DOI: 10.19080/GJARM.2018.06.555685.
In article an attempt of systematization of the neurophysiological changes observed at a special form of schizophrenia by means of a new technique - dispersion of amplitude-frequency characteristics of an alpha rhythm of EEG - for the purpose of identification of the general regularities of development of psychopathology, search of new neurophysiological forms of schizophrenia and differential its mentally retarded diagnostics and autism is made.
Keywords: Neurophysiological Features of Schizophrenia; Entropy of the Neuron-Glial Network of the Brain; Dispersion of Alpha-Rhythm; Diagnosis of Mental Illness
Abbreviations: NGNB: Neuron-Glial Network of the brain; HVT: Hyperventilation Test; DAFCAR EEG: Dispersion of Amplitude-Frequency Characteristics of an Alpha Rhythm of EEG; DNPD: Detector of Neuro Mental Disorders
The problem of search of a new paradigm of psychiatry consists not only in separate disagreements of specialists in an occasion of clinical distinctions of separate nosological forms of mental diseases. It is necessary to understand what the cornerstone of psychopathological patterns is. And it is possible to understand it only having learned by what changes in neural and glial network of a brain (NGNB) they are followed. Sometimes on this way absolutely unexpected circumstances open. The problem which will be stated in this article rather seldom arises, and, maybe, we too seldom pay to it attention owing to insufficiency of means in official medicine. It is about the main problem diseases of psychiatry - dementia, schizophrenia and autism. In the 19th century the idea about a certain “uniform disease” in psychiatry - “the theory of uniform psychosis” of Grizinger was stated . However, at that time it was not succeeded to prove it as even there is no rather fair idea of the reasons of mental diseases now. In many articles devoted to the matter, the idea expressed that the psychopathology is result of pathological increase of level of entropy of NGNB - the general or regional. “System 3+3”  explaining the psychopathology mechanism was offered:
a) The normal state of mentality - on the basis of reference afferent synthesis is created the system of semantic images of an environmental real, congruent for this look, on the basis of which socially acceptable behavior models of an individual are created
b) The psychopathology - violation of normal process of afferent synthesis, in result of what is created pathological polysemantic of images of an environmental real on the basis of which socially unacceptable behavior models of an individual are formed
c) A marker of process of violation of afferent synthesis is the degree of an entropy of NGNB, which is shown in DAFCAR EEG. The purposes and tasks - identification of new neurophysiological forms of schizophrenia and their differential diagnostics with other mental diseases.
By means of a technique of the analysis of DAFCAR EEG of two patients are studied. The cases represented here are rather rare therefore it is difficult to submit statistics - it is necessary to be limited to the description of two clinical cases. Patients – the man and the woman - about one age, both have a mental diseasesince the childhood and since the childhood contain in psychiatric
boarding schools. Patients were exposed to a standard technique
of performance of EEG with arrangement of electrodes on the
international system “10-20%” and ipsilateral ear electrodes.
HVT was carried out by a standard technique with dispersive
assessment of changes of an alpha rhythm by S.V. Rosman’s
method . The DAFCAR parameters were calculated by S.V.
Rosman’s method by means of the Microsoft Excel and Statistica
12.0 programs .
With both patients the contact as they do not own speech
skills is complicated. Incidents of psychoses were not observed.
Psychological testing is impossible. They spend the most part
of time alone, are interested in nothing. The diagnosis “Deep
intellectual backwardness” is exposed to both. At a research of the
DAFCAR parameters it is established (Figures 1 & 2).
For comparison we give cartograms at typical paranoid
schizophrenia and typical endogenous reaction to HVT at
schizophrenia . Thus, at paranoid schizophrenia increase in
representation is observed medlennovolno-howl parts of a range
of an alpha rhythm with increase of the shift of modal value,
characteristic of schizophrenia, in frontal departments to the left
and the expressed increase of dispersive changes, mainly in frontal
assignments. Thus, in Figures 1 & 2 we see the inverted picture
of dispersive violations of an alpha rhythm in comparison with
paranoid schizophrenia, as allowed to call these cases “the inverse
schizophrenia”. If the data provided in this article are obtained by
clinical confirmations at other researchers, then it is possible to
draw very serious conclusions. Sharp decrease in frequency of an
alpha rhythm is characteristic of deep intellectual backwardness,
as well as of all dementias. There is even a correlation
communication between the frequency of an alpha rhythm and IQ
- the alpha rhythm frequency is lower, the IQ is lower . Thus, the
presented cases are not intellectual backwardness. At the same
time it and not typical schizophrenia owing to the DAFCAR inverse
parameters (Figures 3 & 4). This state is the closest to autism,
however about it there are no researches in the field of DAFCAR.
It is very probable that a certain part of autism is presented by
such conditions of “the inverted schizophrenia” [7-8]. Indirectly
it is confirmed, for example, the fact that at Asperger’s syndrome
sharp acceleration of an alpha rhythm is observed and clinically
observes the expressed intellectual backwardness.
The given cases explain one more fact which did not find
an explanation in official science – growth of autism in the
developed countries, despite good food and education, a healthy
lifestyle and the other benefits of a civilization. The matter is that
in ontogenesis the alpha rhythm gradually accelerates from 3
years approximately on 1 Hz a year. This phenomenon is called
by me “a neurophysiological overсloсking”, by an example of
an overсloсking of the central processing unit of the computer.
This process has to take place with a certain speed and evenly
in all departments of a brain. However often, owing to some
conditions, the uniformity of this acceleration is broken, and most often in frontal departments. When the alpha rhythm in
frontal departments slows down, clinically we observe ADHD
and other behavioural violations, for example, enuresis .
And here the uncontrollable “neurophysiological overсloсking
“, perhaps, leads to autism especially as in the developed
countries information load of children, which can stimulate raises
uncontrollable acceleration of an alpha rhythm in frontal lobes. It
has, sometimes, far-reaching consequences, even when externally
the brain developed evenly – quite often these violations have the
hidden character and come to light only after hyper ventilating
test. Such patients have reduced resistance to a stress and are
capable to deviant behavior – violence, psychoses, addictions.
I give an example of normally organized EEG at the patient who
committed violent crime (Figure 5). To similar neurophysiological
changes in Russian there is a figurative definition: “the roof goes”.
It very precisely reflects a condition of the people enduring the
moment of intense violation of mentality [10-11]. At alcohol
intake or psycho-emotional loading at people with low resistance
to a stress something is observed like a schizophrenic attack with
loss of orientation in time, space and the personality and the
accompanying deviant behavior.
a) By means of the DAАСAR EEG method it is possible to
analyse a condition of NGNB for the purpose of identification
of pathological general and regional increase of its entropy
that is the main reason for psychopathology.
b) There is a possibility of identification of new
pathological conditions of mentality which reason was
unknown earlier. The technique is simple, objective, allows
to establish correlation connection between clinical and
neurophysiological manifestations of mental diseases.
c) The device for screening of psychopathology on the
basis of the DAFCAR EEG parameters - “Detector of Neuropsy
Disorders” (DNPD), which allows to reveal probable belonging
of this pattern of EEG to psychopathological within 5 minutes
d) Use of this device will allow to pass to a 3-landmark
method of identification of psychopathology into populations:
neurophysiological screening, psychological testing,
consultation of the psychiatrist.