Mini Review

Meningeal Sarcomas

Behzad Saberi*

Medical Research, Esfahan, Iran

Submission: December 04, 2019; Published: December 13, 2019

*Corresponding Address: Behzad Saberi, Medical Research, Esfahan, Iran

How to cite this article:Behzad Saberi. Meningeal Sarcomas. Canc Therapy & Oncol Int J. 2019; 15(2): 555910. DOI:10.19080/CTOIJ.2019.15.555910

Mini Review

Mesenchymal tissue is the origin of sarcomas. Brain sarcomas are usually in continuity with the dura. Intraparenchymal sarcomas also exist because the tela choroida and blood vessels have the mesenchymal origin [1]. Metastatic sarcoma is the differential diagnosis of such tumors which requires investigation to find a primary sarcoma in a place outside of the CNS. It is because true intracranial sarcomas are rarely found [2]. Classification of the tumors of the soft tissue which would arise from a site outside of the CNS, would be the base for classifying such tumors pathologically [3,4]. Intracranial sarcomas can be classified into various groups which are distinct from each other including gliosarcoma, sarcoma in the context of meningioma, skull and scalp originated sarcomas with extensions intracranially, de novo primary brain sarcomas, benign tumors which simulate sarcomas like desmoplastic infantile ganglio-glioma, benign fibrous histiocytoma and superficial cerebral astrocytoma, metastases from primary tumors which are located outside of the brain and post CNS radiotherapy treatment sarcomas [5-8].

Radical surgical excision would be the treatment method for such tumors. Chemotherapy and radiotherapy can be added to the surgical treatment. These tumors have high rates of brain invasion which such parenchymal invasions require the unaffected part of the brain to be sacrificed, in case of surgical trying for total excision of the tumors. Even with trying for aggressive resection of the tumors, local recurrence would happen. Also, metastatic disease is common in such tumors. These make the survival periods of the patients with such tumors short.

References

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