Generalized Idiopathic Annular Granuloma in a Child Successfully Treated with Retinoids
M Bennani*, S Benkirane, S Elloudi, H Baybay, Z Douhi and FZ Mernissi
Dermatology department of Hassan II University Hospital Center, Morocco
Submission: January 21, 2020; Published:March 04, 2020
*Corresponding author:M Bennani Dermatology Department of Hassan II University Hospital Center, Fez, Morocco
How to cite this article:M Bennani, S Benkirane, S Elloudi, H Baybay, Z Douhi, et al. Generalized Idiopathic Annular Granuloma in a Child Successfully Treated with Retinoids. Curr Trends Clin Med Imaging. 2020; 4(1): 555626. DOI: 10.19080/CTCMI.2020.04.555626
Keywords: Idiopathic; Annular granuloma; Retinoids; Abnormalities; Topical corticosteroid
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A 12-year-old child with no notable pathological ATCD, including no notion of personal or family diabetes, and no similar case in the family. Since the age of 4, he had rapidly extensive, asymptomatic erythematous lesions. The clinical examination showed multiple erythematous and yellowish papules, some of which were in the annular arrangement of the elbows, wrists, backs of the hands and feet, ankles, knees and thighs in a bilateral and symmetrical manner (Figure 1), and other confluences in a large protruding cupboard in the neck and back (Figure 2), without palmoplantar involvement. The rest of the clinical examination was normal. The patient was already treated with topical corticosteroid without improvement.
A biopsy of an annular lesion of the back of the hand objectified: an aspect in favor of a generalized granular granuloma. All the etiologic assessment was without abnormalities, especially no diabetes or dyslipidemia, no underlying neoplasia, and all viral serologies were negative. Treatment with retinoids was started at a dose of 5 mg / day and then an increase of doses at 10 mg / day. The evolution was marked by a disinfiltration of the lesions, and the disappearance of more than 80% after 1 year of treatment without the appearance of new lesions.