The word-phyto/herb refers to plants while -some means cell like. Herbosomes are lipid compatible molecular complex. It is a fresh approach to drug delivery system which addresses the limitations of the conventional drug delivery systems. Phytosomes contain the bioactive phytoconstituents of herb extract bounded by lipids. Phytosomes are developed by incorporating standardized plant extract or water soluble bioactive plant constituent into phospholipids to make lipid compatible molecular complex called phytosomes and so progress their absorption and bioavailability. Phytosome method produce a cell which is a expensive component of herbal extract which protected from damage by digestive secretion and gut microbes .
As compare to conventional herbal formulation, Phytosomes have following advantages:
I. It enhance the absorption of lipid insoluble polar phytoconstituents through oral as well as topical way showing improved bioavailability, therefore extensively better therapeutic profit.
II. When the absorption of active constituent(s) is enhanced, its quantity requirement is too reduced.
III. Chemical bonds are created between phosphatidylcholine molecule and phytoconstituent, consequently the phytosomes prove improved stability outline.
IV. Additional nutritional profit of phospholipids.
V. Considerable drug entrapment.
VI. Application of phytoconstituents in form of phytosome improves their percutaneous absorption and act as functional cosmetics.
VII. Phytosome process produces a little cell whereby the costly components of the herbal extract are sheltered from damage by digestive secretions and gut bacteria.
Like to phytosomes, a liposome is a combination of hydrophilic material and phosphatidylcholine in a specific ratio, with a water soluble substance is bounded by phosphatidylcholine molecule. In comparison, phytosomes is a combination of water soluble entity and phosphatidylcholine produced in the ratio of 1:1 or 2:1 molecular complex with chemical bonding between phytoconstituents and phosphatidylcholine. Phytosome have proved to be efficient in topical and skin care products than liposomes .