| Table 3: Effect of Ethanolic extract of Hamelia patens leaf on yeast induced hyperpyrexia in rats. Each value is the mean ± S.E.M. of 5 rats. *P < 0.05; **p < 0.01 compared with control; student’s t-test. |
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Groups |
Dose (mg / kg) |
Pre-Drug Temp (°C) |
Post Drug Temp (60min) |
Post Drug Temp (90min) |
Post Drug Temp (120min)
|
Hamelia patens leaf extract |
50 |
38.4± 0.3 |
38.3± 0.3 |
38.2± 0.3 |
37.9± 0.3
|
Hamelia patens leaf extract |
100 |
38.2± 0.4 |
37.8± 0.4 |
37.6± 0.5 |
37.0± 0.2*
|
Hamelia patens leaf extract |
200 |
38.5± 0.3 |
37.6± 0.2 |
37.1± 0.1** |
36.6± 0.3**
|
Hamelia patens leaf extract |
150 |
38.5± 0.3 |
37.5± 0.4* |
37.1± 0.4* |
36.9± 0.4*
|