| Table 2: Effect of Ethanolic extracts of Hamelia patens leaves on hot plate test in rats. Each value is the mean ± S.E.M. of 5 rats.* P < 0.05; **p < 0.01, compared with control; student’s t-test. |
|||
Groups |
Dose (mg / kg) Orally |
Licking time (sec) a |
|
Early phase |
Late phase |
||
Control (Saline) |
- |
77.4 ± 9.4 |
61.8 ± 7.58 |
Hamelia patens leaf extract |
50 |
54.4 ± 3.2* |
32.8 ± 4.3* |
Hamelia patens leaf extract |
100 |
36.4 ± 2.8** |
31.8 ± 7.0* |
Hamelia patens leaf extract |
200 |
33.6 ± 4.4** |
29.2 ± 4.4* |
Diclofenac sodium |
5 |
40.4 ± 3.3* |
37.5 ± 4.7 * |