| Table 1: Effect of formulation parameters on the particle size, polydispersity index, drug loading and encapsulation efficiency of CS-MIAA coated magnetic nanoparticles. | |||||
Drug input (mg) |
Chitosan concentration (mg/ml) |
MIAA concentration (mmol) |
Particle size (nm) |
Polydispersity index |
Drug loading (%)
|
5 |
2 |
8 |
23.2 ± 1.98 |
0.19 ± 0.25 |
30 ± 2.75
|
10 |
2 |
8 |
23.2 ± 1.98 |
0.19 ± 0.25 |
34.5 ± 3.12
|
10 |
2 |
15 |
21.8 ± 2.09 |
0.17 ± 0.03 |
36 ± 2.95
|
10 |
2 |
18 |
25.5 ± 1.56 |
0.25 ± 0.03 |
32.5 ± 3.01
|
10 |
2 |
22 |
28.3 + 2.54 |
0.41 ± 0.04 |
35 ± 3.42
|
10 |
2 |
30 |
32.4 ±2.95 |
0.46 ± 0.06 |
37.5 ± 2.85
|