QUANTUM-INFORMATIONAL MACROPHENOMENA IN BIOMEDICINE & HOLISTIC PSYCHOSOMATICS: QUANTUM-HOLOGRAPHIC FRAMEWORK

. The Hopfield-like quantum-holographic framework for macroscopic quantum phenomena in biomolecular folding, integrative medicine, transpersonal psychology, and holistic psychosomatics is outlined. This might have significant implications for better understanding of quantum-holographic feedback control mechanisms of morphogenesis, and healing boundary conditions in acupuncture-based and consciousness-based


Quantum Biology -Biomolecules and Cells
In the context of macroscopic quantum phenomena of the second kind [22], we proposed a quantum-decoherence and quantum-holographic (QDQH) approach to conformational transitions of biomolecules [2] (which cannot be considered kinetically understood on the basis of (semi) classical predictions: the so-called Levinthal paradox [23]). It seems that our solution-inprinciple of the long-lasting Levinthal paradox offers a natural physical picture of a series of processes with biomolecules including chain folding and biomolecular recognition in an open biological environment. So, in quantum world of biomolecules, fluctuations between noncomplementary (approximately isolated) biomolecular states of energy and (environmentdecoherence-selected non-isolated) biomolecular states of conformation are being repeated. At the level of open cell, our QDQH approach also allows the system of identical non-interacting and dynamically uncoupled proteins of a particular type (and their biomolecular targets) to be considered as a global spatial quantum ensemble of identical processors, whose time-adapting density of conformational states can be presented as a cellular Hopfield-like quantum-holographic neural network [2]. To generalize, a series of all kinds of intracellular and extracellular environment-driven local biochemically-coupled reactions could be equivalently quantumholographically considered as a global Haken-like neural network composed of a number of corresponding layers of Hopfield-like quantum-holographic associative neural networks (with the extension to the higher hierarchical levels of the organism, this possibly being the missing 'downward causation' (epi)genetic control mechanism of morphogenesis and psychosomatics based on acupuncture and consciousness, cf. also next section on quantum medicine).

Quantum Medicine -Three Front Lines
Holistic approach to integrative medicine [4,7] and transpersonal psychology [4,19] is of particular importance because of their ever-increasing use in developed countries -since modern research into psychosomatic diseases indicates the need to apply holistic methods (with a focus on body's acupuncture system and consciousness [4]), oriented to treating a person as a whole (including mental environment), implying their macroscopic quantum origin -with significant global implications. Thus, our extended QDQH approach implies three fronts lines of psychosomatic integrative medicine in top-down order [5]: (i) spirituality and circular (psycho / energy) therapies from all relevant meta-positions (with the potential for permanent removal of mutual memory attractors at the level of collective consciousness, for the purpose of energyinformation dis-entanglement of mental addresses of persons involved in the problem); (ii) (quantum) holistic medicine and non-circular (psycho / energy) therapies (temporarily removing memory attractors at the level of the acupuncture system / individual consciousness and preventing or alleviating their somatization as a consequence of neglect on the first front line); and (iii) conventional symptomatic medicine (which through the immunology, pharmacology, preventive diagnostics and surgery at the somatic level prevents or alleviates the somatized consequences of neglect in the first two front lines). It should be pointed out that necessary activities in the second and third levels, with neglect of the first level, would result in further transpersonal transfer of memory attractors on the level of individual and collective consciousness in this and future generations. So, this implies necessity to focus on the origins of many psychosomatic problems on underlying prenatal trans-generational levels (cf. [15][16][17][18] and refs therein).

Quantum Psychology -Two Cognitive Modes
Our extended QDQH research also implies two modes of knowledge (as preserved in many traditions!), according to the coupling strength consciousness-body-environment [5,[15][16][17][18]: (i) weakly-coupled direct mode (in out-of-body spiritually-creative quantum-entangled nonstationary transitional states of consciousness / quantum-coherent stationary altered states of consciousness, like prayer, meditation, daydreams, lucid dreams, deep creative insights...); and (ii) strongly-coupled indirect mode (in bodily perceptively-rationally mediated classically-reduced stationary normal states of consciousness, like sensory perception, logic and scientific reasoning...) -with important spiritual-epistemological implications. And can help us realize that all our partial rationalizations (classically-reduced mappings!) are just approximations of fundamentally-holistic reality (quantum-holographic territory!), and that all divisions are tragic misunderstanding of spiritually immature epoch of civilization (as map is not the territory!). The mentioned considerations include three essential comparative holistic aspects (cf. [5,[15][16][17][18] and refs therein): (i) utility (of transpersonal spiritual practices in the healing or the salvation of souls); (ii) epistemology (of mystical and rational modes of knowledge); and (iii) phenomenology (of transpersonal spiritual experiences). This is in line with re-awakened interest in fundamental and applied holistic research in past decades, anticipating the occurrence of grand synthesis of two modes of knowledge in the framework of extended QDQH paradigm -where the role of each individual becomes indispensable due to the influence and care for collective mental environment and social well-being. All this indicates the full significance of holistic education and behaviordemonstrating ultimate necessity of redefining the global educational / informational / political goals, with the shift towards holistic gentle actions for global solutions of the world risk society.

Psychosomatic Energy-Informational System -Three Aspects
Finally, three aspects of psychosomatic acupuncture system / consciousness / vital energy should be pointed out (cf. [5,[15][16][17][18] and refs therein): (i) quasi-classical ionic aspect of acupuncture system (suggested by research of the non-threshold electrical synapses, which have shown an order of magnitude increased concentration at acupuncture points, that is consistent with a much lower electrical resistance of acupuncture points compared to the surrounding tissue, as well as a significantly higher absorption of ions in these points); (ii) quantum-informational electromagnetic aspect of acupuncture system (indicated by quantum-coherent characteristics of Russian-Ukrainian school of microwave resonance therapy, and discovery that any quantum system has formal mathematical structure of Hopfield-like quantum-holographic associative neural network; it is also pointed out that acupuncture s sy ys st te em m is at least psychosomatically related to consciousness, as supported by very effective meridian (psycho / energy) therapies with successive setting new boundary conditions in acupuncture s sy ys st te em m during emotionally-involved visualizations of psychosomatic problems); and (iii) transpersonal exotic aspect of energyinformational communications (known in all traditions, and now widely used in transpersonal energy therapies (such as Qigong, Reiki, Pranic healing...) -through established and stabilized energy-informational channels of vital energy (qi, ki, prana...) -pointing to a deeper exotic spacetime nature of these energy-informational channels of vital energy (i.e. connection with exotic quantum vacuum fluctuations, necessary for anti-gravitational stabilization of the space-time channels)). So, it seems that multidisciplinary research on crossroad of psychosomatic integrative medicine and quantum informatics may become fruitful in spreading frontiers of the existing scientific paradigm.

Conclusions
The Hopfield-like quantum-holographic framework for macroscopic quantum phenomena in biomolecular folding, integrative medicine, transpersonal psychology, and holistic psychosomatics is outlined. This might have significant implications for better understanding of quantum-holographic feedback control mechanisms of morphogenesis, and healing boundary conditions in acupuncture-based and consciousness-based holistic psychosomatics.